GL-3 (RETA) Weight Loss Molecule and Consultation

GL-3 Molecule (Prescription Only) - 10mg 

Triple-Incretin Therapy for Maximum Fat Loss, Appetite Control & Metabolic Reset

Formulation

GL-3 Core 10: 1mL vial containing 10mg total GL-3
Concentration: 10mg / 1mL

Classification: Prescription Only – Requires Provider Consultation & Approval

What Is GL-3 Therapy?

GL-3 is a prescription triple-incretin therapy that activates three key metabolic pathways:

• GLP-1 (glucagon-like peptide-1)

• GIP (glucose-dependent insulinotropic polypeptide)

• Glucagon receptor

By targeting all three receptors simultaneously, GL-3 provides comprehensive metabolic signaling, leading to:

• Significant appetite suppression

• Accelerated fat loss

• Improved insulin sensitivity

• Increased energy expenditure

GL-3 represents the most advanced tier of incretin-based therapy and is typically utilized for patients requiring provider-directed, high-efficiency fat loss and metabolic intervention.

All GL-3 products require clinical consultation and prescription approval prior to dispensing.

🔬 Key Research-Based Mechanisms

🔥 Triple-Incretin Activation for Superior Fat Loss
Simultaneous activation of GLP-1, GIP, and glucagon receptors enhances satiety and drives adipose tissue reduction.
Jastreboff et al., 2023 (NEJM) – Demonstrated up to 24.2% total body-weight reduction over 48 weeks.

🩸 Improved Glycemic Control & Insulin Sensitivity
Reduces fasting glucose, improves insulin signaling, and lowers HbA1c.
Frias et al., 2023 (Diabetes Care) – Reported HbA1c reductions up to 2.2%.

🧠 Appetite Suppression & Craving Control
Reduces central appetite signaling and food reward pathways.
Killion et al., 2022 – Demonstrated reduced hedonic eating behavior in preclinical models.

🧬 Increased Fat Oxidation & Energy Expenditure
Glucagon receptor activation increases metabolic rate and fat utilization.
Gil-Lozano et al., 2021 – Showed preservation of metabolic rate with increased fat oxidation.

⚕️ Clinical Access & Prescription Protocol

GL-3 therapy requires provider oversight and prescription approval.

• Telehealth consultation required prior to dispensing

• Labs may be recommended (HbA1c, fasting glucose, lipid panel, IGF-1)

• Individualized dosing and titration plan

• Ongoing provider monitoring and follow-up included

💉 Dosing Protocol (GL-3 Core 10)

• Total Dose: 10mg per vial

• Concentration: 10mg / 1mL

• 10 units = 1mg GL-3

Starting Dose:

• 20 units weekly (2mg)

Titration Strategy:

• Maintain dose until 2 consecutive weeks of no weight loss

• Then increase by 10 units (1mg)

• If side effects occur, reduce dose by 10 units and reassess

Route: Subcutaneous injection (abdomen preferred)
Duration: ~2–5 weeks per vial
Program Length: 3–6 months with reassessment every 4–8 weeks

Compatible Stacks

• KPV – inflammation and gut support

• Tesamorelin – visceral fat targeting

• MOTS-C – metabolic efficiency and insulin sensitivity

• GHK-Cu – recovery and tissue support

📦 What’s Included With Every Order

• 1 × GL-3 Core 10 vial (10mg / 1mL)

• Pre-measured bacteriostatic water

• Insulin syringes & alcohol swabs

• Sharps container bag

• Printed dosing, titration, storage, and injection guide

• Ongoing access to licensed prescribing provider

📧 Need Assistance?

Admin@Propeptides.com
480-400-6225

🛡️ Advanced Fat Loss. Triple-Pathway Precision. Clinical Oversight.

GL-3 Core 10 is designed for patients who want high-efficiency metabolic intervention with structured medical guidance. By activating three complementary incretin pathways, it delivers powerful, controlled fat loss with ongoing clinical support.

Start with GL-3 Core 10 and build a protocol tailored to your metabolic goals.