GL-3 (RETA) Weight Loss Molecule and Consultation - 50mg/5mL

GL-3 Molecule (Prescription Only)- 50mg

Triple-Incretin Therapy for Maximum Fat Loss, Appetite Control & Metabolic Reset

Formulation

GL-3 Core 50: 5mL vial containing 50mg total GL-3
Concentration: 10mg / 1mL

Classification: Prescription Only – Requires Provider Consultation & Approval

What Is GL-3 Therapy?

GL-3 is a prescription triple-incretin therapy that activates three key metabolic pathways:

• GLP-1 (glucagon-like peptide-1)

• GIP (glucose-dependent insulinotropic polypeptide)

• Glucagon receptor

By targeting all three receptors simultaneously, GL-3 provides comprehensive metabolic signaling, leading to:

• Significant appetite suppression

• Accelerated fat loss

• Improved insulin sensitivity

• Increased energy expenditure

GL-3 represents the most advanced tier of incretin-based therapy and is typically utilized for patients requiring longer-term, provider-directed metabolic intervention and sustained fat loss.

All GL-3 products require clinical consultation and prescription approval prior to dispensing.

🔬 Key Research-Based Mechanisms

🔥 Triple-Incretin Activation for Superior Fat Loss
Simultaneous activation of GLP-1, GIP, and glucagon receptors enhances satiety and drives adipose tissue reduction.
Jastreboff et al., 2023 (NEJM) – Demonstrated up to 24.2% total body-weight reduction over 48 weeks.

🩸 Improved Glycemic Control & Insulin Sensitivity
Reduces fasting glucose, improves insulin signaling, and lowers HbA1c.
Frias et al., 2023 (Diabetes Care) – Reported HbA1c reductions up to 2.2%.

🧠 Appetite Suppression & Craving Control
Reduces central appetite signaling and food reward pathways.
Killion et al., 2022 – Demonstrated reduced hedonic eating behavior in preclinical models.

🧬 Increased Fat Oxidation & Energy Expenditure
Glucagon receptor activation increases metabolic rate and fat utilization.
Gil-Lozano et al., 2021 – Showed preservation of metabolic rate with increased fat oxidation.

⚕️ Clinical Access & Prescription Protocol

GL-3 therapy requires provider oversight and prescription approval.

• Telehealth consultation required prior to dispensing

• Labs may be recommended (HbA1c, fasting glucose, lipid panel, IGF-1)

• Individualized dosing and titration plan

• Ongoing provider monitoring and follow-up included

💉 Dosing Protocol (GL-3 Core 50)

• Total Dose: 50mg per vial

• Concentration: 10mg / 1mL

• 10 units = 1mg GL-3

Starting Dose:

• 20 units weekly (2mg)

Titration Strategy (Standard PROpeptides Protocol):

• Maintain dose until 2 consecutive weeks of no weight loss

• Then increase by 10 units (1mg)

• If side effects occur, reduce dose by 10 units, then resume titration

Route: Subcutaneous injection (abdomen preferred)

Estimated Duration:

• ~8–12+ weeks depending on dosing progression

Program Length:

• 3–6 months with reassessment every 4–8 weeks

Compatible Stacks

• KPV – inflammation and gut support

• Tesamorelin – visceral fat targeting

• MOTS-C – metabolic efficiency and insulin sensitivity

• GHK-Cu – recovery and tissue support

📦 What’s Included With Every Order

• 1 × GL-3 Core 50 vial (50mg / 5mL)

• Pre-measured bacteriostatic water

• Insulin syringes & alcohol swabs

• Sharps container bag

• Printed dosing, titration, storage, and injection guide

• Ongoing access to licensed prescribing provider

📧 Need Assistance?

Admin@Propeptides.com
480-400-6225

🛡️ Advanced Fat Loss. Triple-Pathway Precision. Clinical Oversight.

GL-3 Core 50 is designed for patients committed to long-term metabolic transformation. With extended dosing capacity and structured titration, it allows for sustained fat loss, improved metabolic function, and consistent clinical oversight.

Commit to GL-3 Core 50 for a complete, provider-guided metabolic program.